On Monday, Chatham-Kent police received a citizen tip that a wanted man was leaving a business on St. Clair Street in Chatham in a van.Officers found and stopped that vehicle on Oldfield Line near Prince Albert Road.Police said the man, a passenger in the vehicle, was wanted for failing to comply with his release conditions, property-related offences, assault with a weapon, administering a noxious substance and failing to attend court.The 24-year-old Walpole Island man was arrested and taken to the courthouse pending a bail hearing.Failing to complyOn Sept. 9, a woman was released from court with several conditions, including an order to reside at a specific Chatham address.On Sept. 21, officers visited this address to conduct a compliance check. At this time, officers learned the woman was no longer living there, police said.Police found the woman Monday night on Forest Street and she was arrested.The 23-year-old woman of no fixed address was charged with failing to comply with her release conditions. She has been held pending a bail hearing.Breach of curfewJust before midnight on Monday, an officer reportedly saw a man riding his bicycle with improper lighting on Murray Street near Margaret Avenue in Wallaceburg.The officer stopped the man for this Highway Traffic Act offence.The man was also reportedly bound by a curfew and wanted for breaching his probation, property-related offences and failing to attend court.The 50-year-old Wallaceburg man was arrested and charged with failing to comply with his curfew. He was held for bail.Theft of building materialsSome time between Sunday at 6 p.m. and Monday at 8 a.m., someone entered a building under construction on Queen Street in Chatham and stole six sheets of 4’x9′ silver board and 25 pieces of 2’x4′ lumber.The total value of the theft was estimated at $1,000. Anyone with information is asked to contact Const. Doug Cowell at firstname.lastname@example.org or 519-436-6600 ext. 83666. Anonymous callers may call Crime Stoppers at 1-800-222-TIPS (8477) and may be eligible for a cash reward.Theft of golf clubsSome time between Sept. 25 and Sept. 28, someone entered a garage on Dahlia Drive and stole a set of Callaway golf clubs valued at $1,000.Anyone with information is asked to contact Const. Branden Grellmore at email@example.com or 519-436-6600 ext. 8107343, or Crime Stoppers.Peace officer memorial serviceThis Sunday at 10:30 a.m., a service will take place at Praise Fellowship Church on Park Avenue East in Chatham to remember first responders who have died in the line of duty.All are welcome to attend.
In an article entitled The Return of Monetized Eyeballs, Om Malik values BoingBoing at $34 million – calculated at $38 per unique monthly website visitor (the average purchase price per unique user of acquisitions during the past year). John Battelle, who manages BoingBoing, thinks that figure is off because it’d be hard to make that investment back on a site which has “fierce attitudes about content and the author/audience relationship”.Now Jason Calacanis, who recently pocketed a large sum of money by selling weblogsinc to AOL, has come out and said BoingBoing’s value is closer to “between 500k and $3M”. Jason wrote:“Boingboing, like any other web property, is worth 1-10x revenue and 5-30x earnings. So, if BB does 30-50k a month/360-600k a year (which seems possible to me based on the ~5m page views a month) it would be worth between 500k and $3M (based on revenue since with five mouths and server hosting to pay for it doesn’t really have earnings–yet!). Those numbers fall into line with my calculation of a really loyal user being worth $1-3.”Personally I like Om’s numbers better, because it makes me a multimillionaire on paper. But I suspect Jason’s figures tell a few home truths about what it takes to actually do a deal. On the other hand, eyeballs still seems to be the currency of choice in the Web world – bubble or not. How many current Web 2.0 companies are earning decent revenue? Perhaps that only goes to prove Jason’s point, that it’s all bubble talk. I’ll stop now before I get totally out of my depth – financial analysis not being my forte. But I’m interested in what people have to say about it. Who do you think is closer to the mark – Om (eyeballs, $34M for BB) or Jason (revenue, earnings, 500k-$3M for BB)? Top Reasons to Go With Managed WordPress Hosting richard macmanus 8 Best WordPress Hosting Solutions on the Market Why Tech Companies Need Simpler Terms of Servic… A Web Developer’s New Best Friend is the AI Wai… Related Posts Tags:#business#web
With the Nehalem architecture-based processor server/workstation launch just around the corner, customers are demonstrating how quickly they can take advantage of the performance afforded to them by our newest processor. One recent example was a Philips* CT demonstration of a beating heart at the major European IT show, CeBit*. According to the Philips demonstration, they were able to render the human heart twice as fast using our upcoming Nehalem workstation processors as compared to the previous generation Intel® Xeon® processor 54xx series. Check out the beating heart demonstration video in this link using our Nehalem architecture-based workstation processor.For those of us with no medical background, 3D imaging is a tool enabling doctors to visualize the human body without invasive tools. The patient is scanned, data is acquired, and a 3D model is assembled and they are able to show what going on in the human body without touching it. CT tools are able to produce thousand of pictures or slices per second. This results in large datasets that take time to process. Software running on a server or workstation processes this vast amount of data to generate detailed 3D images and then can be interpreted by medical staff. The primary challenge is managing large datasets generated by large volume acquisitions while speeding time to diagnosis.The heart is a particularly challenging to visualize using CT scanning. It is a very fast moving organ, with little control over its movement because is involuntary, and the heart needs to be frozen in time to get accurate anatomical picture. Another challenge for volume rendering is high level image quality necessary so that anatomical structures of the heart can be depicted in an accurate way.One interesting aspect of Philips CT solution is that image rendering takes place in the in the CPU which means that the performance of their solution is not restricted to by the memory available on a graphics card and is not slowed down by transfer of data between the CPU and the graphics card. The Philips’ rendering software is multi-threaded and is able to take advantage of Intel advances in multi-threading /multi-core processing technology and software optimization tools for best performance improvements.I believe Philips’ demonstration is just one example of how Nehalem architecture-based processors will provide meaningful advances in 3D visualization, not just in medical fields, but other areas such as manufacturing and digital content creation.Jimmy Leon*Other names and brands may be claimed as the property of others.
But none has made quite as good a story as that of VTS-270, a potential treatment for the rare, incurable, inherited disease Niemann-Pick type C-1 (NPC). It was shepherded through early development by an NCATS-orchestrated collaboration and then handed off to the small Gaithersburg, Maryland, company, Vtesse. Now, however, an early chapter in that story is getting a rewrite that raises questions about whether participants in the collaboration downplayed a key setback.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Vtesse is currently running a late-stage clinical trial of the drug, a large sugar molecule known as a cyclodextrin, in which it is injected by lumbar puncture into the spinal fluid of children with the disease (see “Why are people fighting over a promising treatment for a fatal childhood disease”). However, there was a big bump along the road to the current trial, when the NCATS-convened team, in a first attempt, injected the drug directly into the brain ventricles—the cisterns that hold cerebrospinal fluid—using an implanted reservoir normally deployed to inject brain cancer chemotherapy. The reservoirs of two of three children quickly became infected and the trial was put on clinical hold on 30 April 2013.That study—called an ICV trial for “intracerebroventricular” drug administration—is back in the limelight because a mother of two children afflicted with NPC recently asked for a correction in an article that appeared in the journal Current Topics in Medicinal Chemistry. Written by 25 authors, it described the collaboration between government, academic researchers, and disease advocacy groups that led to the ICV trial as a model of the teamwork that can speed drugs through early development, boosting their chances of being commercialized. The paper was submitted to the journal 9 days after the trial was put on clinical hold, was revised 2 months later, and was not published until 2014. However, it nowhere mentions the failure of the trial and the abandonment of the direct brain route of administration. Chris Hempel, the mother of 12-year-old twin girls with NPC and a prominent figure among advocates for development of NPC therapies, last week pointed out the omission to the journal’s editor, Allen Reitz in Doylestown, Pennsylvania. (One of Hempel’s daughters suffered a stroke after ICV administration of cyclodextrin, although not as part of the NIH trial; it was being administered separately under a compassionate use protocol approved by the Food and Drug Administration.) Reitz now says he is preparing to run a correction. It will read:“It has come to our attention that at the time of submission of this manuscript and during peer review that the Phase I Clinical Trial as described involving ICV administration using an Ommaya reservoir was in fact already on clinical hold. Dr. [Elizabeth] Ottinger, senior author on this paper, has updated the clinical status of this program to say that the trial was subsequently resumed using the intrathecal (IT) route of administration.” In an email to Science, Reitz added: “Even though the focus of the paper was on the collaboration, which is a good thing, and the paper was well-written, the authors had a responsibility to accurately represent the state of the collaboration at that point in time.” Reitz emphasizes, however, that the physicians running the trial did quickly make the information public. In a 45-minute conference call convened by the National Niemann-Pick Disease Foundation 3 days after the trial was put on hold, they updated NPC parents about the setback and the hold.Austin and the other authors believe the correction is unnecessary. He wrote to Science: “The theme of the particular issue of the journal in which the article was published was collaborative science, and therefore the article was focused on the process and collaborative environment contributing to the development of the drug. The information regarding the clinical trial is currently being written for submission to a research journal. The senior authors did not agree with the published corrigendum, and albeit to no avail, explicitly had asked the editor for the opportunity of a discussion before he published it.” When Francis Collins, the director of the National Institutes of Health (NIH), proposed a new translational medicine center at NIH 5 years ago, he met with plenty of skepticism. Former Merck & Co. CEO Roy Vagelos told a congressional committee that the idea that the $600 million NIH effort could surmount drug development problems that industry has failed to solve was like believing “in fairies.”So Chris Austin, the Collins protégé who has run the National Center for Advancing Translational Sciences (NCATS) in Bethesda, Maryland, since soon after its launch, has been under plenty of pressure to produce success stories. And NCATS has had some, such as the discovery that an existing antihistamine, chlorcyclizine, blocks the ability of the hepatitis C virus to infect cells. Through a brute-force chemical screen in the midst of the 2014 Ebola epidemic, NCATS researchers also identified 53 compounds that block that virus from entering cells.
“Tiger must be there,” Johnson said. “Because there’s 40 people instead of four.”Golf Channel added an hour of coverage, and Twitter came alive with people curious about the latest return. That included Steph Curry, the Golden State Warriors’ two-time MVP who played a Web.com Tour event in August. “The wait is over. The wait is over,” he tweeted .Michael Phelps said he was “pumped to be watching” Woods on TV again.This event doesn’t draw big crowds, but most of them were with Woods to see how he would fare in this latest comeback, this one from fusion surgery on his lower back on April 20. Given it was his fourth surgery in three years, coupled with a DUI arrest in the summer that exposed the struggles Woods was having with pain medicine, a day like this seemed a long way off.Woods said he appreciated the moment Thursday morning.“I was in my head thanking all the people who have helped me in giving me a chance to come back and play this round again,” he said. “There were a lot of people who were instrumental in my life — friends, outside people I’ve never met before, obviously my surgeon. I was very thankful.”And he was as competitive as always.Woods delivered his first fist pump on par-4 fourth hole when he scooped a chip that didn’t reach the green, and then holed an 18-foot par putt.While the field is short, the competition is strong with eight of the top in the world at Albany. Woodsrealizes they have spent the last couple of years playing at a high level that allows them to overcome a few mistakes.“I don’t want to lose shots,” Woods said. “I haven’t played in a very long time and I can’t afford to go out there and make a bunch of bogeys and know that I can make nine, 10 birdies and offset them.” Russia signals rainbow flags tolerated at World Cup MRT 7 on track for partial opening in 2021 Don’t miss out on the latest news and information. View comments Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Malditas save PH from shutout MOST READ After his best shot of the day — a pitching wedge he hit low from 95 yards that settled a foot behind the hole for birdie on No. 14 — he sent a drive well to the right into the native dunes. Woods had to take a penalty drop to get back in play and wound up making bogey.But it was solid enough that Woods was far more interested in the leaderboard than the fact he felt strong physically.“It was not only nice to get the first round out of the way, but also I’m only three shots out of the lead,” he said. “So to be able to put myself there after not playing for 10 months or so, it was nice to feel the adrenaline out there.”He was tied for eighth in the 18-man field of this holiday exhibition that awards world ranking points but does not count as official on any tour. Rickie Fowler and Matt Kuchar were at 67, while Dustin Johnson, Jordan Spieth, Justin Rose and Kevin Chappell were at 68.The buzz was back. Johnson noticed it when he was on the practice range and noticed a crowd around theputting green.ADVERTISEMENT Along with his five birdies — only two of them were tap-ins — Woods had an assortment of tough par saves, including a 10-footer that kept him dropping another shot on a par 5 at No. 11. He finished his round with a belly wedge from short of the 17th green because of mud on his ball, and holing a 6-foot par putt on the 18th.A year ago, Woods made a pair of double bogeys over the last three holes for a 73 to finish nine shots behind. This time, he closed with pars and was three back.PGA champion Justin Thomas, who also opened with a 69 in the same pairing with Woods, is among those whohave played with him in recent weeks in Florida. Woods said he once played nine straight days.“It was what I saw when we played at home,” Thomas said. “Obviously, taking this much time off from competition is hard. I felt rusty starting after a month-and-a-half, so I can’t imagine what it felt like for him. But he played well.”Sports Related Videospowered by AdSparcRead Next Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games Jordan delivers on promise: 2 Cobra choppers now in PH “For me, I thought I did great,” Woods said with a smile.And in a sign that he was ready to get back into the mix, he was far from satisfied.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingUnlike a year ago, when Woods ended a 15-month hiatus from his ailing back, he didn’t show any fatigue at the end of his round or make any big numbers. His only regret was playing the par 5s at Albany Golf Club in 1-over par with two bogeys that stalled his momentum.Coming off a 25-foot birdie putt on the par-3 eighth, Woods hit a 3-wood that rolled up on the green and then down a slope about 30 feet from the pin. It took him four shots from there, starting with a chip that didn’t reach the green and his first expletive loud enough for television to pick up. Tiger Woods prepares to hit from the second fairway at the Hero World Challenge golf tournament at Albany Golf Club in Nassau, Bahamas, Thursday, Nov. 30, 2017. (AP Photo/Dante Carrer)NASSAU, Bahamas — Tiger Woods looked a lot better in his return to golf than he did when he left.Playing for the first time since his fourth back surgery, Woods returned from a 10-month layoff with a 3-under 69 on a breezy Thursday in the Bahamas that left him three shots behind Tommy Fleetwood after the opening round of the Hero World Challenge.ADVERTISEMENT ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims LATEST STORIES After 30 years, Johnlu Koa still doing ‘hard-to-make’ quality breads Hotel says PH coach apologized for ‘kikiam for breakfast’ claim The Fatted Calf and Ayutthaya: New restos worth the drive to Tagaytay